Cannabis and Pregnancy
Researchers have documented significant risks associated with using cannabis while pregnant. Because of this, the American Academy of Pediatrics and the American College of Obstetricians and Gynecologists recommend that women not use cannabis while they are trying to get pregnant, during pregnancy, and while they are breastfeeding.1,2 It is extremely important for new mothers using medical cannabis to coordinate care between the doctor recommending their cannabis use and their pediatrician.
There is no research confirming that cannabis use during pregnancy is safe
Cannabis is the most used non-medical drug during pregnancy.2 People who are pregnant report using cannabis to relieve pregnancy-related symptoms; to treat nausea and appetite changes,33 improve mood,6 alleviate anxiety or depression,32 and relieve pain.19 Many use cannabis during pregnancy because they believe that it is safer than prescribed medications and they prefer “natural” remedies.1 However, there is no research confirming that this is a safe practice.
Using cannabis while pregnant can harm the baby
Fully understanding the effects of cannabis on the developing fetus has been difficult because of research limitations, and because those who use it often use other drugs as well, like alcohol and tobacco.2, 14, 20 Social and environmental factors such as lack of access to healthcare, poor nutrition, and exposure to domestic violence can affect the baby’s growth and development.2 These additional factors make it hard to know if negative pre- and post-natal health outcomes are because of cannabis use or other substances.
We do know that tetrahydrocannabinol (THC), the psychoactive or mind-altering ingredient in cannabis, crosses the placenta to the fetus.31 There is strong evidence that smoking cannabis while pregnant causes lower birth weight.23 A recent study found prenatal cannabis exposure to cause smaller head circumference,18 particularly for those who use throughout their entire pregnancy.8 Healthy birth weight and head circumference is important for brain development, good health in childhood, and long-term health into adulthood. Other risks may include a greater risk of stillbirth,28 preterm birth (being born before 37 weeks gestation),19 and increased admission to the neonatal intensive care unit (NICU).23
There is some evidence that prenatal cannabis exposure affects learning and memory,26 problem solving skills, motor coordination, and ability to analyze visual objects (e.g., data, art, maps).30,9,11,5 Additional studies have found that prenatal cannabis exposure is associated with a lower attention span and behavioral problems.10,13 Also, those who were exposed to cannabis while in the uterus are more likely to use cannabis by age 14, even when other factors that influence drug use are considered.7
Secondhand cannabis smoke is harmful to the baby
The THC in secondhand smoke may be passed to infants and children.29 Secondhand cannabis smoke has many of the same cancer-causing chemicals found in tobacco smoke.21 Visit our Secondhand Cannabis Smoke page to learn more.
Babies are exposed to cannabis through breastmilk
The impact of cannabis use on breastfeeding infants is still not fully understood. However, there are potential risks of exposure to cannabis through breastmilk. One study found that both THC and CBD were found in breastmilk shortly after the mother used cannabis, whether by smoking or eating it, and could stay in the breastmilk for up to 1-2 days.22 THC stays in the body longer because it combines with fat in the body which is processed more slowly.2 High concentrations of THC can accumulate in human breastmilk when cannabis is used regularly.22 THC consumed in breastmilk could affect a baby’s developing brain. One study found decreased motor development at 1 year of age in children exposed to THC through breastmilk in the first month of life.3 The long-term effects of exposure to THC through breastmilk are unknown.
Breastfeeding mothers are encouraged to avoid using cannabis while nursing to prevent potential health risks to their infant.1
Cannabis use may affect fertility
Studies about the effect of cannabis use on fertility have conflicting results.17 In women, there is evidence that cannabis use may disrupt the menstrual cycle causing women to not ovulate.15 Cannabis use may also decrease successful egg retrieval and fertilization through in vitro fertilization (IVF).16 Similarly, research about the effect of cannabis use on male reproductive health have had mixed results. Some studies show that cannabis use negatively affects a male’s ability to get erect and orgasm and may cause premature or delayed ejaculation.25,27 Other studies have not confirmed these findings.4 Heavy cannabis use can also negatively affect sperm count and function.12 Cannabis use in both males and females may make it difficult to get pregnant.
References
- American Academy of Pediatrics (AAP). Policy statement: Breastfeeding and the use of human milk. Pediatrics (2022) 150 (1): e2022057988. View statement
- American College of Obstetricians and Gynecologists (ACOG), Committee on Obstetric Practice: Committee Opinion on Marijuana use During Pregnancy and Lactation. Number 722, October 2017. Reaffirmed in 2021. Free online
- Astley, S. J., & Little, R. E. (1990). Maternal marijuana use during lactation and infant development at one year. Neurotoxicology and teratology, 12(2), 161–168. https://doi.org/10.1016/0892-0362(90)90129-z
- Bhambhvani, H. P., Kasman, A. M., Wilson-King, G., & Eisenberg, M. L. (2020). A Survey Exploring the Relationship Between Cannabis Use Characteristics and Sexual Function in Men. Sexual medicine, 8(3), 436–445. https://doi.org/10.1016/j.esxm.2020.06.002
- Chandler, L. S., Richardson, G. A., Gallagher, J. D., & Day, N. L. (1996). Prenatal exposure to alcohol and marijuana: effects on motor development of preschool children. Alcoholism, clinical and experimental research, 20(3), 455–461. https://doi.org/10.1111/j.1530-0277.1996.tb01075.x
- Chang JC, Tarr JA, Holland CL, et al. Beliefs and Attitudes Regarding Prenatal Marijuana Use: Perspectives of Pregnant Women Who Report Use. Drug Alcohol Depend. 2019;196:14-20. doi:10.1016/j.drugalcdep.2018.11.028. Epub 2019 Jan 11. PMID: 30658220; PMCID: PMC6756431.
- Day, N. L., Goldschmidt, L., & Thomas, C. A. (2006). Prenatal marijuana exposure contributes to the prediction of marijuana use at age 14. Addiction (Abingdon, England), 101(9), 1313–1322. https://doi.org/10.1111/j.1360-0443.2006.01523.x
- Dodge, P., Nadolski, K., Kopkau, H., Zablocki, V., Forrestal, K., & Bailey, B. A. (2023). The impact of timing of in utero marijuana exposure on fetal growth. Frontiers in pediatrics, 11, 1103749. https://doi.org/10.3389/fped.2023.1103749
- Fried, P. A., & Watkinson, B. (2000). Visuoperceptual functioning differs in 9- to 12-year olds prenatally exposed to cigarettes and marihuana. Neurotoxicology and teratology, 22(1), 11–20. https://doi.org/10.1016/s0892-0362(99)00046-x
- Fried, P. A., & Watkinson, B. (2001). Differential effects on facets of attention in adolescents prenatally exposed to cigarettes and marihuana. Neurotoxicology and teratology, 23(5), 421–430. https://doi.org/10.1016/s0892-0362(01)00160-x
- Fried, P. A., Watkinson, B., & Gray, R. (2003). Differential effects on cognitive functioning in 13- to 16-year-olds prenatally exposed to cigarettes and marihuana. Neurotoxicology and teratology, 25(4), 427–436. https://doi.org/10.1016/s0892-0362(03)00029-1
- Fronczak CM, Kim ED, Barqawi AB. The insults of illicit drug use on male fertility [Review]. Journal of Andrology 2012;33(4):515-528. Free online
- Goldschmidt, L., Day, N. L., & Richardson, G. A. (2000). Effects of prenatal marijuana exposure on child behavior problems at age 10. Neurotoxicology and teratology, 22(3), 325–336. https://doi.org/10.1016/s0892-0362(00)00066-0
- Jaques SC, et al. Cannabis, the pregnant woman and her child: Weeding out the myths. Journal of Perinatology 2014;34:417-424. View abstract
- Jukic, A. M., Weinberg, C. R., Baird, D. D., & Wilcox, A. J. (2007). Lifestyle and reproductive factors associated with follicular phase length. Journal of women’s health (2002), 16(9), 1340–1347. https://doi.org/10.1089/jwh.2007.0354
- Klonoff-Cohen, H. S., Natarajan, L., & Chen, R. V. (2006). A prospective study of the effects of female and male marijuana use on in vitro fertilization (IVF) and gamete intrafallopian transfer (GIFT) outcomes. American journal of obstetrics and gynecology, 194(2), 369–376. https://doi.org/10.1016/j.ajog.2005.08.020
- Lo, J. O., Hedges, J. C., & Girardi, G. (2022). Impact of cannabinoids on pregnancy, reproductive health, and offspring outcomes. American journal of obstetrics and gynecology, 227(4), 571–581. https://doi.org/10.1016/j.ajog.2022.05.056
- Marchand, G., Masoud, A. T., Govindan, M., Ware, K., King, A., Ruther, S., Brazil, G., Ulibarri, H., Parise, J., Arroyo, A., Coriell, C., Goetz, S., Karrys, A., & Sainz, K. (2022). Birth Outcomes of Neonates Exposed to Marijuana in Utero: A Systematic Review and Meta-analysis. JAMA network open, 5(1), e2145653. https://doi.org/10.1001/jamanetworkopen.2021.45653Mark K, Desai A, Terplan M. Marijuana use and pregnancy: prevalence, associated characteristics, and birth outcomes. Arch Womens Ment Health. 2016;19(1):105-111. doi:10.1007/s00737-015-0529-9
- McKenzie LB, Keim SA, Klebanoff MA. Risk Perceptions about Cannabis Use and Receipt of Health-Related Information during Pregnancy. Am J Health Promot. 2022 Nov;36(8):1316-1325. doi: 10.1177/08901171221099496. Epub 2022 May 5. PMID: 35512115; PMCID: PMC9617780.
- Metz, T. D., & Stickrath, E. H. (2015). Marijuana use in pregnancy and lactation: a review of the evidence. American journal of obstetrics and gynecology, 213(6), 761–778. https://doi.org/10.1016/j.ajog.2015.05.025
- Moir, D., Rickert, W. S., Levasseur, G., Larose, Y., Maertens, R., White, P., & Desjardins, S. (2008). A comparison of mainstream and sidestream marijuana and tobacco cigarette smoke produced under two machine smoking conditions. Chemical research in toxicology, 21(2), 494–502. https://doi.org/10.1021/tx700275p
- Moss, M. J., Bushlin, I., Kazmierczak, S., Koop, D., Hendrickson, R. G., Zuckerman, K. E., & Grigsby, T. M. (2021). Cannabis use and measurement of cannabinoids in plasma and breast milk of breastfeeding mothers. Pediatric research, 90(4), 861–868. https://doi.org/10.1038/s41390-020-01332-2
- National Academies of Sciences, Engineering, and Medicine. (2017). Prenatal, Perinatal, and Neonatal Exposure to Cannabis. In The Health Effects of Cannabis and Cannabinoids: The Current State of Evidence and Recommendations for Research (pp.245-250). Washington, DC: The National Academies Press. https://doi.org/10.17226/24625.
- Neonates Exposed to Marijuana in Utero: A Systematic Review and Meta-analysis. JAMA network open, 5(1), e2145653. https://doi.org/10.1001/jamanetworkopen.2021.45653
- Pizzol, D., Demurtas, J., Stubbs, B., Soysal, P., Mason, C., Isik, A. T., Solmi, M., Smith, L., & Veronese, N. (2019). Relationship Between Cannabis Use and Erectile Dysfunction: A Systematic Review and Meta-Analysis. American journal of men’s health, 13(6), 1557988319892464. https://doi.org/10.1177/1557988319892464
- Richardson, G. A., Ryan, C., Willford, J., Day, N. L., & Goldschmidt, L. (2002). Prenatal alcohol and marijuana exposure: effects on neuropsychological outcomes at 10 years. Neurotoxicology and teratology, 24(3), 309–320. https://doi.org/10.1016/s0892-0362(02)00193-9
- Smith, A. M., Ferris, J. A., Simpson, J. M., Shelley, J., Pitts, M. K., & Richters, J. (2010). Cannabis use and sexual health. The journal of sexual medicine, 7(2 Pt 1), 787–793. https://doi.org/10.1111/j.1743-6109.2009.01453.x
- Tobacco, drug use in pregnancy can double risk of stillbirth. https://www.nichd.nih.gov/newsroom/releases/121113-stillbirth-drug-use Accessed January 19, 2024
- Wilson KM, Torok MR, Wei B, Wang L, Robinson M, Sosnoff CS, Blount BC. Detecting biomarkers of secondhand marijuana smoke in young children. Pediatr Res. 2017 Apr;81(4):589-592.
- Willford, J. A., Chandler, L. S., Goldschmidt, L., & Day, N. L. (2010). Effects of prenatal tobacco, alcohol and marijuana exposure on processing speed, visual-motor coordination, and interhemispheric transfer. Neurotoxicology and teratology, 32(6), 580–588. https://doi.org/10.1016/j.ntt.2010.06.004
- Wu CS, Jew CP,Lu, HC. Lasting impacts of prenatal cannabis exposure and the role of endogenous cannabinoids in the developing brain. Future Neurology 2011;6(4): 459–480. Free online
- Young-Wolff KC, Gali K, Sarovar V, Rutledge GW, Prochaska JJ. Women’s Questions About Perinatal Cannabis Use and Healthcare Providers’ Responses. J Womens Health (Larchmt). 2020;29(7):919-926. doi:10.1089/jwh.2019.8112. Epub 2020 Jan 30.PMID: 32011205; PMCID: PMC7371546.
- Young-Wolff KC, Sarovar V, Tucker LY, et al. Association of Nausea and Vomiting in Pregnancy with Prenatal Marijuana Use. JAMA Intern Med. 2018;178(10):1423-1424. doi:10.1001/jamainternmed.2018.3581. PMID: 30128499; PMCID: PMC6233758.
Last updated 2024.